Consumption from Potassium, Magnesium, Calcium, and Dietary fiber and Chance of Coronary attack Among us Men

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Consumption regarding Potassium, Magnesium, Calcium supplements, and Fibre and you may Threat of Heart attack Among us Males

From the Divisions away from Nutrients (Good.A good., Age.B.R., E.L.Grams., Yards.J.S., W.C.W.), Epidemiology (A good.Good., Elizabeth.B.Roentgen., Meters.A.H., Yards.J.S., W.C.W.), and Health insurance and Personal Choices (I.K.), Harvard College or university from Societal Health, and Channing Lab, Service off Treatments, Harvard Medical College or university and you can Brigham and you may Ladies Medical (Age.B.Roentgen., E.L.Grams., M.J.S., W.C.W., I.K.), Boston, Mass.

Consumption out of Potassium, Magnesium, Calcium, and you will Fiber and you can Chance of Stroke In our midst Guys

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Intake out-of Potassium, Magnesium, Calcium supplements, and you may Dietary fiber and you may Likelihood of Heart attack Among us Men

About Departments out of Nutrients (A good.Good., Elizabeth.B.Roentgen., Elizabeth.L.G., M.J.S., W.C.W.), Epidemiology (Good.A good., Age.B.R., Meters.A beneficial.H., Meters.J.S., W.C.W.), and you will Health insurance and Public Decisions (I.K.), Harvard University off Social Health, while the Channing Laboratory, Department out of Medication, Harvard Medical University and you will Brigham and you will Ladies Healthcare (Elizabeth.B.R., Elizabeth.L.Grams., Meters.J.S., W.C.W., We.K.), Boston, Bulk.

Intake regarding Potassium, Magnesium, Calcium, and you can Fibre and Threat of Coronary attack In our midst Guys

About Departments out of Nutrition (An effective.A., Age.B.Roentgen., Age.L.G., Meters.J.S., W.C.W.), Epidemiology (A beneficial.An excellent., Elizabeth.B.R., Yards.A great.H., Yards.J.S., W.C.W.), and you will Health and Personal Behavior (I.K.), Harvard College or university out of Societal Health, plus the Channing Research, Agencies off Treatments, Harvard Medical College or university and you will Brigham and you can Ladies Healthcare (Age.B.Roentgen., Elizabeth.L.G., Meters.J.S., W.C.W., We.K.), Boston, Mass.

Consumption of Potassium, Magnesium, Calcium supplements, and you can Soluble fiber and you may Chance of Heart attack Among us Guys

On the Divisions off Nutrition (An excellent.An excellent., Elizabeth.B.Roentgen., E.L.G., M.J.S., W.C.W.), Epidemiology (A beneficial.A beneficial., E.B.Roentgen., Meters.Good.H., Meters.J.S., W.C.W.), and Health insurance and Personal Conclusion (We.K.), Harvard College or university off Personal Wellness, as well as the Channing Lab, Company out-of Drug, Harvard Medical University and you will Brigham and you will Ladies‘ Health (Elizabeth.B.R., E.L.G., Meters.J.S., W.C.W., I.K.), Boston, Size.

Consumption off Potassium, Magnesium, Calcium supplements, and you can Fibre and Chance of Stroke In our midst Guys

Regarding Departments away from Diet (A.An effective., E.B.Roentgen., Age.L.Grams., Yards.J.S., W.C.W.), Epidemiology (An excellent.A good., Elizabeth.B.R., M.A great.H., M.J.S., W.C.W.), and you may Health insurance and Public Choices (I.K.), Harvard College or university out of Societal Fitness, and the Channing Research, Service away from Medicine, Harvard Scientific College or university and Brigham and you will Ladies Hospital (Age.B.R., Age.L.Grams., Meters.J.S., W.C.W., We.K.), Boston, Mass.

Abstract

Background-Creature studies and epidemiological studies have ideal you to highest potassium consumption may slow down the chance of coronary arrest, however the evidence was inconclusive, and the part of most other nourishment within the potassium-rich edibles stays unfamiliar.

Actions and Efficiency-We looked at the newest connection of potassium and relevant nutrition which have exposure off stroke certainly one of 43 738 United states males, forty in order to 75 yrs old, in place of recognized cardio diseases otherwise all forms of diabetes, just who accomplished a good semiquantitative dinner frequency survey from inside the 1986. Through the 8 many years of go after-up, 328 strokes (210 ischemic, 70 hemorrhagic, 48 unspecified) had been reported. The fresh new multivariate cousin chance of coronary arrest of any sort for males about best fifth of potassium intake (median intake, 4.step 3 grams/d) in the place of those who work in the bottom (median, 2.4 g/d) was 0.62 (95% CI, 0.43, 0.88; P to own development=0.007). Results for ischemic coronary arrest by yourself had been comparable. Consumption off cereal fibre and you can magnesium, although not off calcium, was indeed and additionally inversely regarding the threat of total heart attack. Such inverse contacts was most of the stronger into the hypertensive than just normotensive males and you will just weren’t materially changed by changes having blood pressure. Access to potassium capsules has also been inversely associated with likelihood of stroke, such as among men delivering diuretics (relative risk, 0.36; 95% CI, 0.18, 0.72).

Conclusions-In the event this type of studies do not establish good causal relationship, they are consistent with the theory one to diets rich in potassium, magnesium, and cereal soluble fiber reduce the likelihood of coronary arrest, particularly one of hypertensive boys. Potassium medicine could be helpful, but on account of hazards, explore will be cautiously tracked and you can restricted to guys delivering potassium-losing diuretics.