In the current study, the association of new BP categories with risk of incident CVD was more evident in young adults aged <40 years than in the older subjects, which is in line with earlier studies that also reported a stronger association between BP and CVD outcomes in middle?aged compared with elderly populations. 8 , 46 , 51 , 52 , 53 The reasons for the stronger associations in young adults are unclear.

The end result out-of BP to the danger of CVD may be toned down that have expanding years due to the fact the prevalence of large BP and you may other CVD chance items also be more commonplace as we age

Within the South Korea, the fresh Korean People of Hypertension determined to use the prior blood pressure level standards from systolic BP/diastolic BP ? mm Hg on account of deficiencies in clear research for additional make use of decreasing the blood pressure threshold so you’re able to mm Hg to possess Koreans. 54 , 55 Depending on the Korean Blood pressure level Truth Layer 2018, exactly how many anybody identified as having blood pressure level improved off step three mil in the 2002 to eight.nine million in 2016, in just 5.seven million those with appropriate and you will persistent antihypertensive therapy inside the 2016. 56 The therapy rates improved off 22% inside the 1998 to 59% for the 2007 and also to 61% for the 2016, and handle price increased out of 5% in the 1998 to 41% during the 2007 in order to 44% within the 2016. 56 When you look at the research conducted recently by using the Korean National Health insurance and Nourishment Examination Questionnaire, the fresh frequency regarding hypertension therefore the quantity of people who require antihypertensive procedures could well be improved, becoming similar along with other countries. 55 , 57 , 58 Centered on present degree handling implementation of the newest direction when you look at the several regions, such as the All of us, Asia, and Korea, this new 2017 ACC/AHA hypertension advice have a tendency to markedly boost the prevalence off blood pressure levels and you can the amount of patients who are in need of antihypertensive procedures initiation and people who are in need of treatment intensification all over the world. 57 , 58 , 59 , 60 , 61 , 62 Inside research conducted recently about Federal Health insurance and Nourishment Examination Questionnaire, with regards to the 2017 ACC/AHA guideline, in contrast to the latest 7th Joint National Panel guideline, the latest incidence from blood pressure level has increased out of 29.9% in order to forty five.6%, the part of All of us adults suitable for antihypertensive procedures has increased away from 34.3% to thirty six.2%, and you may 53.4% of us people providing antihypertensive therapy need alot more extreme decline in their BP. 59 In the event of China, adoption of your own 2017 ACC/AHA hypertension guidance do lead to the increment on prevalence off blood pressure levels of twenty-five% so you’re https://datingranking.net/tr/wapa-inceleme/ able to fifty%. 63 It ought to be examined when the instance changes in the symptomatic endurance and you can healing aim out of so you’re able to mm Hg would increase BP handle and its related consequences. Coming scientific studies are and additionally had a need to confirm this new association ranging from BP and you can CVD chance in the more youthful society that have varied ethnicity and you will to determine if for example the chance/work for ratio for treatment solutions are advantageous contained in this low?risk classification.

This and intercourse standardization was did utilising the lead approach into decades design of Korean population, aged 20 to help you 80 age, in the year 2010

The strengths of our study are its cohort study design, the large sample size, the use of carefully standardized clinical procedures, and the almost complete follow?up for CVD events, as the National Health Insurance collects all medical services use covering the entire Korean population. This study also has several limitations. First, as with most previous studies, the determination of BP was based on a single?day measurement, although 3 readings were taken. Second, we did not incorporate changes in BP categories and other covariates during follow?up. Third, health behaviors were assessed via a self?administered structured questionnaire used in health checkup programs in Korea, as part of the National Health Insurance plan. Measurement errors in these variables may introduce some degree of residual confounding, similar to most epidemiologic studies. Fourth, we used the Pooled Cohorts Equations in all participants; however, it was not validated in adults aged <40 years. Finally, this is an opportunistic cohort of individuals, who self?presented for the health examination, and hence is not a representative sample of low cardiovascular risk young adults in the community. The study population of this cohort was relatively highly educated, young to middle?aged Korean adults with high accessibility to healthcare resources. We compared our study population with a representative sample of the general Korean population (the Korea National Health and Nutrition Examination Survey). The age? and sex?standardized prevalence of hypertension (defined as systolic BP ?140 mm Hg, diastolic BP ?90 mm Hg, or the use of antihypertensive medication), type 2 diabetes mellitus (defined as fasting serum glucose level ?126 mg/dL or the use of blood glucose–lowering agents), obesity (body mass index ?25 kg/m 2 ), and current smoker was lower than those of the general population (16.6% versus 29.1%, 9.3% versus 10.5%, 27.6% versus 31.5%, and 16.8% versus 26.5%, respectively), indicating that our study population may be healthier than the general Korean population. Thus, our findings might not be generalizable to other ethnic groups or populations with different age, demographic, diet, and health behavior characteristics.