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The fresh cardiac myocytes is low in count and start to become elongated within the contour that have age [120, 121]
Cellular transform
That is of this enhanced term throughout the cardiac myocytes from particles including atrial natriuretic peptide (ANP) and you can growth items particularly angiotensin II [122, 123]. This leads to a beneficial decay into the myosin calcium ATPase passion, ultimately causing a general change in intracellular calcium homeostasis and you can following extended contractibility of your cardiac looks and possibly diastolic dysfunction. Read the rest of this entry »